Cover Story: Bioimaging: From Molecules to Organisms

• New Optical Microscopy Techniques and Applications
  Advances in optical-imaging technology offer opportunities in scientific research at the levels of the molecule, cell, tissue, and organism.

• Image-Guided Spectroscopy
  Two Singapore-developed techniques allow fluorescence imaging with simultaneous spectroscopic analysis for investigating molecular dynamics.

• 3D-Squared Microscopy
  Light-sheet-based microscopes pave the way for a new approach to molecular cell biology.

• Bioimaging Zebrafish
  Developmental biology of small fish provides a good model for studying human gene function.

• Seeing Life
  Microscopy, supplemented with fluorescent tags, gives a peek into processes within living cells.

• Better Optical Tomography
  Beam scanning and wide-field configurations provide non-invasive clinical diagnostics with different benefits.

• New Endoscopic Technology Detects Cancer
  Confocal endomicroscopy allows early cancer diagnosis.

• MRI Opens Up Biomedical Research
  MRI offers a whole range of useful applications in science and medicine.

• Non-Invasive Examination of Internal Structure and Function
  The Singapore Synchrotron Light Source offers sophisticated imaging facilities for researching natural processes and deep-lying structures.

• Microscopy with Protons
  The world's most advanced proton microscope looks at the role of trace elements in degenerative disease.

• Medical Imaging and Visualisation Toolkit
  A generic toolkit allows image manipulation and tool development in different environments.

• HCA-Vision Dissects Neuron Images
  A new high-content-analysis program permits complex query to unlock information in nerve-cell images.

• Digital Image Restoration
  New methods reconstruct degraded images.

• Interactive Biomedical Image Viewing
  Three intuitive user-interface prototypes improve 3D-image manipulation.

• Processing Kidney Segmentation in MRI
  New methodology building tool automates MRI processing of kidney images.

• An Eye into Cardiovascular Problems
  The Singapore "I" Vessel Assessment System predicts risk of stroke and heart disease.

• Shedding Light on Skin Disorders
  Time-lapse fluorescence microscopy provides clues to skin disease that may lead to potential new therapies.

• Insight into Blood Flow
  An enhanced laser-speckle technique speeds up the capture and processing of vascular images.

• Bioimaging Defence Functions of the Respiratory Tract
  A fresh approach to observing particle clearance from the airway can help diagnose respiratory problems.

Features

• SmartShelf System
  RFID tracks status of items on shelves in real time.

• Public Innovators
  Civil service shows off innovative ideas having commercial feasibility.

• Instant Face Recognition
  Biometric software overcomes problems of lighting and facial-expression changes.

• Contact Lenses Treat Eye Disease
  Nanostructured lens delivers drugs with little waste and minimal side effects.

• Mapping Body Fats
  Database of lipids and their pathways provides a research platform for studying fat-linked disease.

• Turning on Genetic "Software"
  Gene control by activating or silencing holds promise for cancer and stem-cell therapies.

• Tools to Detect Diseases Early
  Nanotechnology-based tools facilitate early detection of cancer and other diseases.

• Artificial Reef Revitalises Marine Life
  Environment lovers lay down an artificial reef to create thriving marine ecosystems.

Departments

• Editorial
  Visualising Life.

• In Brief
  Innovative highlights in various fields.

• Industry Updates
  Significant developments in industry.

• Spotlight
  Gathering Imaging Expertise under One Umbrella
  Sir George Radda, pioneer in the development of nuclear magnetic resonance for biochemical and clinical investigations, shares his insights and vision as chairman of the Singapore Bioimaging Consortium.

• Viewpoint
  Innovations in Clinical Diagnostic Imaging
  Will sophisticated biomedical-imaging techniques render the X-ray and other radiological methods obsolete?

• Calendar

• Advertiser Index