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By Casey K CHAN
he innumerable connections and intersections of
nanotechnology and other disciplines present considerable
potential for application in diverse fields.
Owing to the nascent stage of development of nanotechnology
and the discordant development in the associated disciplines, many
of these applications are in the exploratory stage, years away from
practical use. It appears, however, that microelectronics and
biotechnology represent two areas in which research results from
nanotechnology can be immediately relevant.
Nanotechnology applied to therapeutic medicine remains
distant. Some people even argue that the idea of nanorobots
coursing through the bloodstream to repair damage resulting from
blood clots and cancer belongs in the realm of science fiction and
will remain so. In reality, nanobiotechnology, the convergence of
nanotechnology and biotechnology, has already given rise to real
practical application in the form of research and diagnostic tools.
Companies in the United States such as Quantum Dot Corp,
Nanosphere Inc and Molecular Nanosystems Inc are shipping or are
close to shipping real products for research and diagnostic use.
Nanobiotechnology offers the potential of obtaining the most
information from the smallest number of test samples in the
shortest time at the lowest possible cost. Nanomaterials are so
small that when they interact with biomolecules they generate
detectable signals in the form of light emissions, a deflection of
a nanoscale cantilever beam or magnetic field.
Currently over 200 molecular diagnostic tests for biomolecules
have become associated with various disease states. Detection of
these biomarkers offers the potential for therapeutic decision,
monitoring the progression of disease, early diagnosis, risk
assessment of predispositions to certain diseases and consequent
preventive care.
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